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CAR-T PSCA Therapy: A New Hope for Castration-Resistant Prostate Cancer
8 novembre 2024

Castration-resistant prostate cancer (mCRPC) presents a major challenge
for healthcare professionals. Despite recent advances, treatment options for
this deadly disease remain limited. CAR-T therapy, which involves modifying
immune cells to specifically target and destroy cancer cells, has shown
promise; however, its effectiveness against solid tumors has yet to be
confirmed.
This study explores the potential of CAR-T cells in treating mCRPC,
specifically targeting the Prostate Stem Cell Antigen (PSCA). The primary
objective is to assess the efficacy, safety, and potential effects of this
approach in addressing the unmet therapeutic needs of patients with mCRPC.
CAR-T PSCA Therapy: Results And Initial Clinical Observations
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Scientific reference
Dorff, T. B., et al (2024). PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer : a phase 1 trial. Nature Medicine, 1-9.
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