2025-03-06
Pregnancy and weight: a winning balance?
Endocrinology and Metabolism
#Obesity #Pregnancy #FatLoss #Nutrition #MaternalHealth
Obesity during pregnancy is a major public health concern, as it is associated with an increased risk of complications for both the mother and the baby. Gestational diabetes raises the likelihood of having a large baby (macrosomia), making delivery more difficult. Hypertensive disorders such as gestational hypertension and preeclampsia can lead to severe complications for both mother and child. Additionally, obesity is a significant risk factor for unplanned cesarean sections due to the obstetric challenges it presents.
Current medical guidelines recommend that obese pregnant women limit their weight gain to between 5 and 9 kg to reduce these risks. However, recent studies suggest that maintaining weight or even experiencing a slight fat loss may be even more beneficial. This approach could improve metabolic markers such as blood glucose levels and blood pressure while ensuring normal fetal growth.
Research on this topic remains limited. The impact of fat loss during pregnancy on the baby and the mother’s long-term health is not yet fully understood. This study investigates the feasibility of such an approach and its effects on obese pregnant women.
This randomized clinical trial, conducted on 100 obese pregnant women in the United States, compared two groups:
The program’s benefits were assessed between weeks 13 and 35 of pregnancy, as well as two weeks postpartum. The study measured key outcomes such as weight and fat mass changes, metabolic health (blood pressure, blood lipid levels, blood glucose, and insulin), and infant safety (fetal growth, newborn size, and body composition). The impact of the intervention on obstetric complications (gestational diabetes, preeclampsia, or unplanned cesarean deliveries) was also analyzed.
The findings show that a supervised weight maintenance and fat loss program during pregnancy is both feasible and beneficial for obese pregnant women. Participants successfully stabilized their weight and reduced fat mass without affecting fetal growth.
Additionally, improvements were observed in insulin sensitivity and blood lipid levels. A slight reduction in blood pressure was also noted, lowering the risk of gestational diabetes and hypertensive disorders. The cesarean section rate was lower in the intervention group. Moreover, adherence to the program was generally good, although some participants faced pregnancy-related challenges such as fatigue and nausea.
These results suggest that this approach could improve both maternal and infant health. However, further studies are needed to confirm its long-term effects.
Obesity during pregnancy is a significant risk factor for both mother and baby, increasing the likelihood of gestational diabetes, hypertensive disorders, and delivery complications. Managing weight in obese pregnant women is challenging, as weight gain must be limited while ensuring optimal fetal growth.
This study investigates the feasibility and impact of a targeted intervention combining nutrition and behavioral support to stabilize weight and reduce fat mass during pregnancy.
The results indicate that this approach is both practical and beneficial. It allowed participants to maintain their weight, improve insulin sensitivity, and reduce metabolic risk factors without compromising the baby’s health. The intervention was also well accepted by most participants.
However, the study has some limitations, including a small sample size and a short follow-up period, which prevent the evaluation of long-term effects on both mother and child. Dietary habits and physical activity could also influence the results and need further investigation.
Larger studies with extended follow-ups are necessary to confirm these benefits and refine recommendations. In the long run, this approach could help reduce obesity-related complications during pregnancy and improve the health of future generations.
Obesity during pregnancy is a major public health concern, as it is associated with an increased risk of complications for both the mother and the baby. Gestational diabetes raises the likelihood of having a large baby (macrosomia), making delivery more difficult. Hypertensive disorders such as gestational hypertension and preeclampsia can lead to severe complications for both mother and child. Additionally, obesity is a significant risk factor for unplanned cesarean sections due to the obstetric challenges it presents.
Current medical guidelines recommend that obese pregnant women limit their weight gain to between 5 and 9 kg to reduce these risks. However, recent studies suggest that maintaining weight or even experiencing a slight fat loss may be even more beneficial. This approach could improve metabolic markers such as blood glucose levels and blood pressure while ensuring normal fetal growth.
Research on this topic remains limited. The impact of fat loss during pregnancy on the baby and the mother’s long-term health is not yet fully understood. This study investigates the feasibility of such an approach and its effects on obese pregnant women.
Losing weight while pregnant: mission possible?
This randomized clinical trial, conducted on 100 obese pregnant women in the United States, compared two groups:
- Control group: Standard medical follow-up by their physician.
- Intervention group: Standard medical follow-up + a weight maintenance and fat loss program, including a controlled dietary plan and behavioral coaching.
The program’s benefits were assessed between weeks 13 and 35 of pregnancy, as well as two weeks postpartum. The study measured key outcomes such as weight and fat mass changes, metabolic health (blood pressure, blood lipid levels, blood glucose, and insulin), and infant safety (fetal growth, newborn size, and body composition). The impact of the intervention on obstetric complications (gestational diabetes, preeclampsia, or unplanned cesarean deliveries) was also analyzed.
The findings show that a supervised weight maintenance and fat loss program during pregnancy is both feasible and beneficial for obese pregnant women. Participants successfully stabilized their weight and reduced fat mass without affecting fetal growth.
Additionally, improvements were observed in insulin sensitivity and blood lipid levels. A slight reduction in blood pressure was also noted, lowering the risk of gestational diabetes and hypertensive disorders. The cesarean section rate was lower in the intervention group. Moreover, adherence to the program was generally good, although some participants faced pregnancy-related challenges such as fatigue and nausea.
These results suggest that this approach could improve both maternal and infant health. However, further studies are needed to confirm its long-term effects.
Read next: Pre-Baby Boost: The Supplements That Make a Difference
A new approach for a healthier pregnancy?
Obesity during pregnancy is a significant risk factor for both mother and baby, increasing the likelihood of gestational diabetes, hypertensive disorders, and delivery complications. Managing weight in obese pregnant women is challenging, as weight gain must be limited while ensuring optimal fetal growth.
This study investigates the feasibility and impact of a targeted intervention combining nutrition and behavioral support to stabilize weight and reduce fat mass during pregnancy.
The results indicate that this approach is both practical and beneficial. It allowed participants to maintain their weight, improve insulin sensitivity, and reduce metabolic risk factors without compromising the baby’s health. The intervention was also well accepted by most participants.
However, the study has some limitations, including a small sample size and a short follow-up period, which prevent the evaluation of long-term effects on both mother and child. Dietary habits and physical activity could also influence the results and need further investigation.
Larger studies with extended follow-ups are necessary to confirm these benefits and refine recommendations. In the long run, this approach could help reduce obesity-related complications during pregnancy and improve the health of future generations.
Read next: Childhood obesity: could homocysteine be the key?

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