Covid-19 in cystic fibrosis patients

Cystic fibrosis patients are considered to be at risk of developing severe forms of respiratory infection. In this study of 171 participants, including 65 with cystic fibrosis, researchers investigated the consequences of Covid-19 and virus-host cell interactions in cystic fibrosis patients, compared with non-cystic fibrosis patients. Symptomatic SARS-CoV2 infections were observed in 8 people with cystic fibrosis (2 of whom required hospitalization) and in 11 people without cystic fibrosis (6 requiring hospitalization). Clinical forms of Covid-19 did not appear to be more severe in cystic fibrosis patients. This could be explained by an unfavorable environment for SARS-CoV2 replication.