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2025-01-28

Pre-Baby Boost: The Supplements That Make a Difference

Public Health and Social Medicine

#PreconceptionNutrition  #MaternalHealth  #MaternalAnemia  #Micronutrients  #IntrauterineGrowth  #GlobalHealth  

Maternal anemia
and malnutrition rank among the leading public health challenges worldwide, affecting millions of women, particularly in low-income countries. These conditions, often linked to limited access to a balanced diet or adequate healthcare, have profound consequences on maternal and neonatal health. Anemia, frequently caused by deficiencies in iron and other micronutrients, reduces the blood's ability to carry oxygen. This leads to persistent fatigue, exacerbates pregnancy-related complications, and sometimes increases the risk of maternal mortality.


For infants, these factors significantly contribute to inadequate intrauterine growth, often resulting in low birth weight. This condition raises the risk of developmental delays and weakens the immune system. These infants face an increased likelihood of long-term complications such as cognitive disorders and stunted growth potential. They are also more prone to developing chronic diseases in adulthood.


The preconception period, encompassing the months before pregnancy, is a critical window for improving maternal and neonatal health. Optimizing nutrition before conception helps prevent deficiencies in women and supports healthy fetal development. Unlike traditional prenatal approaches, which are often reactive, preconception programs offer a proactive and sustainable solution to growing nutritional needs.


This study explores the impact of preconception nutritional supplements on maternal health and birth outcomes, focusing on anemia, fetal growth, and preterm births.
 

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Advanced Supplements for Better Growth?


Twenty trials involving 27,659 women were analyzed, examining the effects of three types of preconception nutritional supplements:
 

  • Iron and folic acid;
  • Multivitamins with multiple micronutrients;
  • Enriched lipid-based supplements combining macro- and micronutrients.
 
The findings reveal that, despite the heterogeneity of the studies, preconception nutritional supplements increased maternal hemoglobin levels by an average of 0.30 g/dL. However, no significant effects were observed on markers of intrauterine growth, such as birth weight, length, or head circumference. Similarly, the supplements did not reduce the risk of small-for-gestational-age births or preterm birth rates. Nonetheless, the benefits of supplementation appeared more pronounced when administered at least three months before conception, underscoring the importance of early intervention to optimize outcomes.  

Read next: A child's neurodevelopment is influenced by diet during pregnancy

Preparing for Pregnancy: A Nutritional Head Start

Maternal anemia, associated with nutritional deficiencies, represents a major public health issue, particularly in low- and middle-income countries. This condition is linked to various pregnancy complications and unfavorable birth outcomes related to inadequate intrauterine growth.  

The study aimed to evaluate the effects of preconception nutritional supplements on pregnancy parameters. Results indicate that these supplements increase maternal hemoglobin levels. However, no significant impact was observed on intrauterine growth or preterm births. These findings highlight the potential of preconception interventions to improve maternal health while underscoring their current limitations.
 

To maximize the impact of preconception nutritional supplements, trials involving diverse cohorts and standardized protocols are essential. Long-term studies are also necessary. Ultimately, integrating preconception nutritional programs into global health policies, with a focus on socio-economic and cultural contexts, could revolutionize current approaches to maternal and neonatal health.  

Read next: Des vitamines pour le moral : le rôle caché des B, C et D !


Source(s) :
Aziz Ali, S., et al. (2025). Role of preconception nutrition supplements in maternal anemia and intrauterine growth: a systematic review and meta-analysis of randomized controlled trials. Systematic reviews, 14(1), 11 ;

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