Acne vulgar and oxidative stress

The links between acne vulgaris and biomarkers of oxidative stress are not clearly established. In this systematic literature review and meta-analysis, researchers explored the links between acne vulgaris and various biomarkers of oxidative stress (superoxide dismutase, malondialdehyde and total antioxidant capacity). A total of 14 trials involving 1,191 participants were included. The data showed that acne vulgaris was associated with malondialdehyde concentrations. Acne vulgaris severity correlated with levels of oxidative stress biomarkers. Total antioxidant capacity was significantly lower in patients with moderate acne vulgaris than in controls.