Press reviews


2025-04-02

Boosting the social brain?

Neurology

#AutismWithoutIntellectualDisability #TMS #SocialCognition #iTBS #Neuroimaging  


Autism spectrum disorders (ASD) are primarily characterized by persistent difficulties in social interaction, communication, and understanding others' intentions. In adults, these social challenges are often pronounced and impact interpersonal relationships, professional life, and overall qu...

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#Autism #Mitochondria #Supplementation #CognitiveFunction #CellularEnergy


Autism spectrum disorders (ASD) are complex neurodevelopmental conditions, characterized by persistent difficulties in social communication, repetitive behaviors, and restricted interests. Their prevalence is steadily increasing—currently affecting 1 in 36 children, with a marked predominance in boys.

D...

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2025-03-31

Immunotherapy on hold?

Allergology and Immunology Oncology

#ColorectalCancer #Immunotherapy #ICI #XL888 #CombinationTherapy  


Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide, especially in advanced stages where treatment options become limited. The advent of immunotherapy, particularly immune checkpoint inhibitors (ICIs), has transformed the treatment landscape of several solid tumors. In...

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2025-03-28

A stress-free pregnancy?

Gynecology

#DeepInfiltratingEndometriosis #Fertility #ColorectalSurgery #FertilityPreservation #Pregnancy  


Deep infiltrating rectal endometriosis (DIRE) represents an advanced and particularly debilitating form of endometriosis, in which lesions infiltrate the rectal wall. It is often associated with severe digestive symptoms (pain during defecation, constipation, diarrhea, sub-o...

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2025-03-28

Move to live better?

Gynecology

#Endometriosis #PelvicPain #PhysicalActivity #MentalHealth #MetaAnalysis


Endometriosis is a chronic, inflammatory gynecological condition characterized by the abnormal presence of endometrial tissue outside the uterine cavity—often on the peritoneum, ovaries, or rectum. It affects about 1 in 10 women of reproductive age and is one of the leading causes of chronic pelvic pain an...

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2025-03-28

Needles for pain relief?

Gynecology

#Endometriosis #Acupuncture #PelvicPain #AlternativeMedicine #MetaAnalysis


Endometriosis is a chronic, inflammatory gynecological disease characterized by the presence of endometrial tissue outside the uterus. It affects nearly 10% of women of reproductive age and often presents with chronic pelvic pain, severe dysmenorrhea, digestive issues, dyspareunia, and infertility. Despi...

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2025-03-26

Spaceflight = Programmed Anemia?

Hematology

#Anemia #Space #Microgravity #Hemolysis #RBC #Astronauts  


Space anemia is a well-known phenomenon among astronauts, observed since the earliest manned missions. It is characterized by a decrease in red blood cell count and hemoglobin concentration, which can affect oxygen transport capacity, physical performance, and post-flight recovery. Until recently, this anemia wa...

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2025-03-25

Kidneys under pressure?

Oncology Nephrology

#ColorectalCancer #AKI #Surgery #OperativeRisk #RiskFactors #PostoperativeCare  


Postoperative acute kidney injury (AKI) is a common complication, particularly following major surgeries such as those performed in digestive oncology. It is associated with increased mortality, prolonged hospital stays, higher readmission rates, and delayed discharge. In the context of...

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2025-03-24

MDR-TB: 9 months to change everything?

Infectiology

#Tuberculosis #MDRTB #OralTreatment #Bedaquiline #Efficacy #Safety  


Multidrug-resistant tuberculosis (MDR-TB) is a particularly concerning form of TB, defined by resistance to isoniazid and rifampicin—the two cornerstone drugs in standard TB treatment. It causes hundreds of thousands of cases worldwide each year and poses a growing threat to public health, especially in...

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2025-03-24

4 months to change everything?

Infectiology

#Tuberculosis  #Diabetes  #Rifapentine  #ShortCourseTreatment  #Moxifloxacin  #Safety


Tuberculosis (TB) and diabetes are two major global public health challenges, with high prevalence and significant impacts on morbidity and mortality. When they coexist in the same patient, these conditions negatively and synergistically interact, making management far m...

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#ColorectalCancer #Chemotherapy #Cetuximab #AntiEGFR #Survival #TargetedTherapy


Metastatic colorectal cancer (mCRC) is an advanced and aggressive form of colorectal cancer characterized by the spread of tumor cells to other organs, particularly the liver and lungs. Its prognosis is poor, with a 5-year survival rate estimated at only 14%, compared to 90% for localized forms. This...

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#Alzheimer  #Genetics  #Neurodegeneration  #PrecisionMedicine  #GWAS  #MultiAncestral


Alzheimer’s disease (AD) is the most common form of dementia, affecting millions worldwide. It is characterized by a progressive decline in cognitive functions, impacting memory, language, and spatial orientation. While environmental factors and lifestyle contribute to i...

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#Delirium  #Surgery  #Melatonin  #Prevention  #Cognition  #Sleep  #Geriatrics  #Anesthesia


Postoperative delirium (POD) is a common disorder in elderly patients following surgery. It manifests as attention, perception, and cognitive disturbances, potentially leading to severe complications. POD increases the risk of cognitive decline, loss of au...

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#Suicide  #VitaminD  #Depression  #Neuroprotection  #Inflammation  #Deficiency  #Supplementation  #Prevention  #MentalHealth  #SuicidalBehavior


Suicide is a major public health issue, causing nearly 700,000 deaths worldwide each year. It results from a combination of biological, psychological, and environmental factors, such as depressi...

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#Fiber  #UremicToxins  #Inflammation  #Microbiota  #Nutrition  #KidneyDisease  #Dialysis


Patients with chronic kidney disease (CKD) often suffer from an imbalance in the gut microbiota, known as dysbiosis. This disruption promotes the proliferation of bacteria that break down dietary proteins and produce uremic toxins (p-cresyl sulfate, indoxyl sulfa...

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