Press reviews
#Leukemia #ALL #AML #Infection #Sepsis #Neurocognition #Memory
Children diagnosed with acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML) are particularly vulnerable to infections due to aggressive treatments that weaken their immune systems. Chemotherapy and corticosteroids reduce natural defenses, while the use of central veno...
Children diagnosed with acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML) are particularly vulnerable to infections due to aggressive treatments that weaken their immune systems. Chemotherapy and corticosteroids reduce natural defenses, while the use of central veno...
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#Leukemia #ALL #cancer #oncology #pediatrics #prophylaxis #immunoglobulin #fever
Acute lymphoblastic laukemia (ALL) is the most common pediatric cancer. Despite therapeutic advances, infections remain a major cause of complications and mortality. Approximately 20% of deaths related to pediatric hematologic cancer treatment are due to infe...
Acute lymphoblastic laukemia (ALL) is the most common pediatric cancer. Despite therapeutic advances, infections remain a major cause of complications and mortality. Approximately 20% of deaths related to pediatric hematologic cancer treatment are due to infe...
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#Leukemia #Cancer #BMI #Obesity #Malnutrition #Oncology
Obesity and malnutrition in children are increasing worldwide. Recent data suggest that these factors may influence the progression of many diseases, including pediatric cancers. Among them, acute leukemia—comprising acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML)—remains the...
Obesity and malnutrition in children are increasing worldwide. Recent data suggest that these factors may influence the progression of many diseases, including pediatric cancers. Among them, acute leukemia—comprising acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML)—remains the...
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#Leukemia #ALL #Oncology #Chemotherapy #Immunotherapy #Innovation
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, accounting for 75% of childhood leukemias. It is characterized by excessive proliferation of immature cells in the bone marrow, preventing normal blood cell production and leading to fatigue, recurrent infect...
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, accounting for 75% of childhood leukemias. It is characterized by excessive proliferation of immature cells in the bone marrow, preventing normal blood cell production and leading to fatigue, recurrent infect...
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#IBD #CrohnsDisease #Biomarker #Gastroenterology #Metabolomics #Lipidomics
Chronic inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are digestive disorders affecting millions worldwide. These conditions are characterized by persistent inflammation of the digestive tract, occurring in flare-ups interspersed with periods of remission. While their...
Chronic inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are digestive disorders affecting millions worldwide. These conditions are characterized by persistent inflammation of the digestive tract, occurring in flare-ups interspersed with periods of remission. While their...
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#Progeria #PrematureAging #CRM1 #Selinexor #Senescence #TargetedTherapy
Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes premature aging. It is triggered by a mutation in the LMNA gene, leading to the abnormal production of progerin. This protein accumulates in the cell nucleus, disrupting cellular function and accelerati...
Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes premature aging. It is triggered by a mutation in the LMNA gene, leading to the abnormal production of progerin. This protein accumulates in the cell nucleus, disrupting cellular function and accelerati...
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#CysticFibrosis #Microbiome #InnovativeTherapies #Probiotics #LungInfections #PrecisionMedicine
Cystic fibrosis is a severe genetic disease caused by mutations in the CFTR gene, disrupting ion transport and leading to thick mucus accumulation in the airways. Despite advances with CFTR modulators, these treatments remain inaccessible to some patients and...
Cystic fibrosis is a severe genetic disease caused by mutations in the CFTR gene, disrupting ion transport and leading to thick mucus accumulation in the airways. Despite advances with CFTR modulators, these treatments remain inaccessible to some patients and...
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#CysticFibrosis #PrecisionMedicine #Lungs #Diagnosis #PersonalizedTherapy
Cystic fibrosis is a hereditary disease caused by mutations in the CFTR gene, leading to a dysfunction in chloride ion transport. This defect results in the production of thick and sticky mucus in multiple organs, particularly the lungs and digestive system. The accumulation of...
Cystic fibrosis is a hereditary disease caused by mutations in the CFTR gene, leading to a dysfunction in chloride ion transport. This defect results in the production of thick and sticky mucus in multiple organs, particularly the lungs and digestive system. The accumulation of...
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#Neurology #CharcotDisease #Neuropathy #CMT2A #MFN2
Charcot-Marie-Tooth disease type 2A (CMT2A) is a rare hereditary sensorimotor neuropathy caused by mutations in the MFN2 gene. Essential for mitochondrial fusion and the proper functioning of peripheral neurons, this protein plays a key role in nerve signal transmission. Its mutation leads to an energy dysfu...
Charcot-Marie-Tooth disease type 2A (CMT2A) is a rare hereditary sensorimotor neuropathy caused by mutations in the MFN2 gene. Essential for mitochondrial fusion and the proper functioning of peripheral neurons, this protein plays a key role in nerve signal transmission. Its mutation leads to an energy dysfu...
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#RareDisease #aHUS #Nephrology #KidneyFailure
Atypical hemolytic uremic syndrome (aHUS) is a rare and severe disease classified under thrombotic microangiopathies (TMA). It results from uncontrolled activation of the alternative complement pathway, leading to endothelial damage, microthrombi formation, and capillary obstruction. This pathological cascade causes non-immun...
Atypical hemolytic uremic syndrome (aHUS) is a rare and severe disease classified under thrombotic microangiopathies (TMA). It results from uncontrolled activation of the alternative complement pathway, leading to endothelial damage, microthrombi formation, and capillary obstruction. This pathological cascade causes non-immun...
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#MicroRNA #Microbiota #IBD #Immunotherapy #Innovation
Chronic inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, are characterized by persistent inflammation of the digestive tract, associated with an imbalance in the gut microbiota. This dysbiosis, combined with an exacerbated immune response, contributes to the chronicity of...
Chronic inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, are characterized by persistent inflammation of the digestive tract, associated with an imbalance in the gut microbiota. This dysbiosis, combined with an exacerbated immune response, contributes to the chronicity of...
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#InfectiousDiseases #Hepatitis #HepatitisB #Immunity #Immunotherapy #Virus
Chronic hepatitis B (HBV) is a persistent viral infection affecting more than 300 million people worldwide. Despite therapeutic advancements, achieving functional cure remains a challenging goal, as current treatments only control viral replication without completely eradicating t...
Chronic hepatitis B (HBV) is a persistent viral infection affecting more than 300 million people worldwide. Despite therapeutic advancements, achieving functional cure remains a challenging goal, as current treatments only control viral replication without completely eradicating t...
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#Poliovirus #InfectiousDiseases #Vaccine #Vaccination #nOPVS2 #Immunity #cVDPV
Circulating vaccine-derived polioviruses (cVDPVs) remain a persistent threat to public health, particularly in regions where vaccination coverage is insufficient. These viruses emerge when the attenuated strain of the oral polio vaccine (OPV) undergoes mutatio...
Circulating vaccine-derived polioviruses (cVDPVs) remain a persistent threat to public health, particularly in regions where vaccination coverage is insufficient. These viruses emerge when the attenuated strain of the oral polio vaccine (OPV) undergoes mutatio...
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#Epilepsy #Surgery #LITT #Neurology #Neurosurgery
Mesial temporal lobe epilepsy (mTLE) is the most common form of drug-resistant focal epilepsy, affecting approximately one-third of epilepsy patients. This condition is characterized by recurrent seizures that do not respond to standard antiepileptic treatments, significantly impacting patients' quality of lif...
Mesial temporal lobe epilepsy (mTLE) is the most common form of drug-resistant focal epilepsy, affecting approximately one-third of epilepsy patients. This condition is characterized by recurrent seizures that do not respond to standard antiepileptic treatments, significantly impacting patients' quality of lif...
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#Cardiology #CongenitalHeartDisease #GeneEnvironmentInteraction #MTHFD1
Congenital heart diseases (CHD) are among the most common birth defects, affecting approximately 1 to 1.2% of newborns. Their origin is multifactorial, resulting from a complex interaction between genetic predispositions and environmental factors. Among the genes involved, MTHFD1 plays...
Congenital heart diseases (CHD) are among the most common birth defects, affecting approximately 1 to 1.2% of newborns. Their origin is multifactorial, resulting from a complex interaction between genetic predispositions and environmental factors. Among the genes involved, MTHFD1 plays...
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